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Year : 2022  |  Volume : 12  |  Issue : 2  |  Page : 65-72

Comparative evaluation of three commercially available local drug delivery medicaments in the treatment of chronic periodontitis

1 Department of Periodontology, Rayat Bahra Dental College and Hospital, Sahibzada Ajit Singh Nagar, India
2 Department of Periodontology, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab, India

Correspondence Address:
Dr. Sumanpreet Kaur Shergill
Near Gurudwara, Tapyana Sahib, Dangarh, Barnala - 148 105, Punjab
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijohs.ijohs_9_22

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Aim: The purpose of the present study was to compare the efficacy of 1.5% chlorhexidine gel, 0.8% hyaluronic acid gel, and 10% doxycycline gel used as an adjunct to scaling and root planning (SRP) and SRP alone in the management of chronic periodontitis. Materials and Methods: Sixteen patients in the age group of 3060 years suffering from chronic periodontitis were selected for the study and divided into four groups. In Group I, after SRP, chlorhexidine gel (chlosite) was inserted up to the base of the pocket. In Group II and III, doxycycline gel and hyaluronic acid gel, respectively, were inserted up to the base of the pocket after SRP, and Group IV was used as a control. The clinical parameters such as probing pocket depth (PPD), relative attachment level (RAL), and gingival index (GI) were recorded at baseline, 6 weeks, and 3 months. Results: There was statistically highly significant improvement in all the clinical parameters at 6 weeks and 3 months when chlorhexidine, doxycycline, and hyaluronic acid gel were used as an adjunct to SRP. Chlosite group showed statistically significant improvement in PPD and RAL as compared to other groups. With regard to GI, Group I showed a statistically significant reduction when compared to Group III (hyaluronic acid group) and IV (control group). However, the reduction was not statistically significant when compared to Group II (doxycycline group). When doxycycline and hyaluronic acid gel were used as an adjunct to SRP, it resulted in greater improvement in clinical parameters as compared to SRP alone, but the results were not statistically significant. Results were comparable for both drugs.

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